Serotonin antagonists

Drugs that block or reverse the actions of serotonin by preventing serotonin from attaching to serotonin receptors.


Any of a class of medications used to treat or prevent nausea and vomiting. Examples are ondansetron (Zofran) and granisetron (Kytril).


A category of medications, also referred to as 5HT3 antagonists, is utilized to manage nausea and vomiting resulting from radiation therapy, chemotherapy, or post-surgical general anesthesia. In these instances, serotonin triggers the brain’s vomiting center, and these drugs counteract the symptoms by blocking serotonin’s action. Widely-used serotonin antagonists include granisetron and ondansetron.


 


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