A potent, short-acting competitive antagonist of mu-opioid receptors in the central nervous system (CNS) with no agonistic effects of its own; the drug of choice in the treatment of narcotic overdose. Naloxone rapidly reverses the toxic and clinical effects of opiates, including respiratory depression, hypotension, and sedation, but it also produces rapid withdrawal symptoms. Its short duration of action (2–4 hours) makes it generally inappropriate for chronic treatment of narcotic addiction. Now available only as generic but may still be known by the discontinued brand name narcan.
A pure, potent, but short-acting narcotic antagonist with no agonistic effects of its own; the drug of choice in the treatment of narcotic overdose. Its short duration of action (2-4 hours) makes it generally inappropriate for chronic treatment of narcotic addiction, but large doses have been used to produce narcotic blockade for up to 18 hours in addicts involved in day- treatment programs.
A narcotic antagonist.
A drug resembling morphine, used in the diagnosis of narcotics addiction and to reverse the effects of narcotics poisoning.
A specific inhibitor of the analgesic properties of the endorphins.
An antinarcotic drug. Naloxone (Narcan) is used to counteract the effects of narcotic-induced impaired breathing, sedation, and lowered blood pressure, whether caused by narcotics or methadone, a narcotic painkiller (often used to treat heroin addiction). Naloxone is also used to diagnose addiction to opiates such as heroin; it is given to a person suspected of being addicted to a drug to see whether the individual experiences withdrawal symptoms.
An effective drug in the treatment of opioid poisoning. It blocks the effects of most opiates; given intravenously, it acts within 2—3 minutes. The drug is also given to newborn babies in the rare instances when their breathing has been depressed by narcotic drugs given to their mothers to relieve pain at a late stage of labour.
An opioid antagonist is a medication that works against the impacts of opioid analgesic drugs. Naloxone, for instance, can undo the respiratory challenges brought about by elevated amounts of opioid medications administered in surgical procedures. Additionally, it can be administered to individuals who have consumed an excessive dose of an opioid drug. Naloxone might also be provided to newborn infants who have been influenced by opioid drugs utilized to alleviate the mother’s discomfort while giving birth.
Potential adverse effects of naloxone encompass queasiness, retching, stomach cramps, diarrhea, and trembling.