Gilles de la Tourette’s syndrome

A genetically determined syndrome usually beginning in early childhood characterized by repetitive tics, other abnormal movements, uncontrolled grunts, unintelligible sounds, and occasionally verbal obscenities. Also known as tourette’s disorder, from part of the last name of Georges Gilles de la Tourette (1857–1904).


Also known as Tourette’s syndrome, this is a hereditary condition of severe and multiple TICS of motor or vocal origin. It usually starts in childhood and becomes chronic (with remissions). With a prevalance of one in 2,000, a dominant gene with variable expression may be responsible. The disorder is associated with explosive vocal tics and grunts, occasionally obscene. The patient may also involuntarily repeat the words or imitate the actions of others. Haloperidol, pimozide (an oral antipsychotic drug similar to chlorpromazine hydrochloride) and clonidine are among drugs that may help to control this distressing, but fortunately rare, disorder.


This is an uncommon inherited neurological disorder passed down through an autosomal dominant gene.


Gilles de la Tourette’s syndrome is more prevalent in males and typically begins in childhood with repetitive grimaces and tics. As the condition advances, involuntary barks, grunts, or other noises may also manifest. In certain cases, the individual may experience episodes of compulsively using foul language, a condition known as coprolalia.


Individuals with Tourette’s syndrome typically experience it throughout their entire lives. In some cases, antipsychotic drugs may be beneficial in alleviating some of the symptoms for certain individuals.


 


Posted

in

by

Tags: