A nonapeptide messenger that is enzymatically produced from kallidin in the blood where it is a potent but short-lived agent of arteriolar dilation and increased capillary permeability. Bradykinin is also released from mast cells during asthma attacks, from gut walls as a gastrointestinal vasodilator, from damaged tissues as a pain signal, and may be a neurotransmitter.
One of a group of naturally present peptides that acts on blood vessels, smooth muscles, and nociceptors.
A chemical produced in the blood when tissues are injured, that plays a role in inflammation.
One of a group of large protein molecules (kinins) that influence the contraction of smooth muscle. The result may be low blood pressure, pain, or changes in normal blood flow.
A naturally occurring polypeptide consisting of nine amino acids. Bradykinin is a very powerful vasodilator and causes contraction of smooth muscle; it is formed in the blood under certain conditions and is thought to play an important role as a mediator of inflammation.
Bradykinin is a substance derived from plasma proteins; it plays an important role in many of the reactions of the body, including inflammation. Its primary action is in producing dilatation of arteries and veins. It has also been described as ‘the most powerful pain-producing agent known’.
Bradykinin, a polypeptide (protein molecule), is naturally produced in the blood as part of the inflammatory response. It serves various functions within the body. Firstly, bradykinin acts as a potent vasodilator, leading to the widening of blood vessels. Additionally, it facilitates the leakage of fluid from blood vessels, stimulates pain receptors, and triggers the contraction of smooth muscles found in internal organs like the lungs or intestines. The presence of bradykinin plays a significant role in the complex mechanisms of inflammation and the associated physiological responses.