The process of the interaction of blood coagulation factors that results in an insoluble fibrin clot.
Process by which liquid blood is changed into a semisolid mass, a blood clot. It can occur in an intact blood vessel, but usually starts with an injury and the exposure of blood. Platelets clump at the wound site. A series of blood proteins, known as clotting factors, undergo chemical changes, leading to the formation of a fibrin meshwork and the trapping of blood cells into a clot. Also called blood clotting. Absence of certain of these clotting factors leads to hemophilia.
The process of clumping together of blood cells to form a clot. This may occur in vitro, intravascularly, or when a laceration of the skin allows the escape of blood from an artery, vein, or capillary. Coagulation of blood may occur in two pathways, depending on the beginning of the process.
The primary process through which blood clots are generated is known as coagulation. This intricate sequence of reactions takes place within the plasma of the blood.