The standard measurement of oral anticoagulation, introduced by the World Health Organization (WHO) in 1983 to replace the prothrombin time (PT). When a patient’s blood is tested to determine its level of anticoagulation, the sample is treated with a thromboplastin, a laboratory reagent that may vary considerably depending on its chemical constituents. As a result, a single sample of blood tested in several different laboratories may give different PT results. To resolve the potential difficulties that this may create for patients who need to achieve a stable level of anticoagulation, the WHO has created the INR to be a rating scale for thromboplastins used around the world that standardizes the PT result.
A standardized formula utilized to adjust variables that influence prothrombin time, ensuring consistent and comparable results across various laboratories and regions. This adjustment is primarily employed for patients undergoing warfarin therapy.
The abbreviation for International Normalized Ratio (INR), a metric employed in the monitoring of anticoagulant drugs. It enables standardized measurement of patients’ anticoagulation status.
A standard set by the World Health Organization to uniformly regulate anticoagulant drug treatment across the globe. This ratio is determined by contrasting the prothrombin time of an individual’s blood with a reference time.