The systemic consequences that result from the splintering of cholesterol-containing plaques from the aorta; when this occurs fragments of cholesterol crystals may travel to and obstruct blood vessels throughout the body. The renal, mesenteric, and femoral arteries are most often affected; involvement of the cerebral vessels is unusual. This condition may arise after trauma to the aorta (e.g., during catheterization or cardiac surgery). It may produce renal failure, and ischemia or infarction of the bowel, toes, or skin. It may ultimately result in death in about half of all affected patients. There is no effective treatment.