A drug that curbs the action of an enzyme in the blood controlling the production of carbonic acid or bicarbonate from carbon dioxide. Called carbonic anhydrase, the enzyme is present in erythrocytes and it has a key part in maintaining the acid-base balance in the blood. Inhibiting drugs include acetazolamide and dorzolamide, and these are used as weak diuretics to reduce the increased intra-ocular pressure in ocular hypertension or open-angle glaucoma.
A group of diuretic medications that hinder the activity of the enzyme carbonic anhydrase, which plays a role in the production of bicarbonate necessary for the generation of aqueous humor by the ciliary tissues in the eye. As a result, the inhibition of this enzyme leads to a decrease in the production of aqueous humor. However, it is important to note that these medications may be associated with certain side effects, including increased urinary frequency, formation of kidney stones, reduced sense of taste, feelings of depression, and anemia.