A blistering disease caused by an autoimmune reaction toward proteins in the skin. Bullous pemphigoid occurs mostly in people older than 60 years. Rigid, possibly tender or itchy blisters appear over multiple body areas. However, unlike pemphigus vulgaris, another blistering disease, bullous pemphigoid does not usually cause lesions in the mouth. Diagnosis is made through biopsy and immunofluorescence studies. Treatment of bullous pemphigoid is with oral corticosteroids and other drugs that suppress the immune system.
A blistering disease found almost exclusively in the elderly. Large, tense bullae filled with clear serum form on normal and urticarial skin. Lesions predominate in the flexural aspects of the limbs and abdomen. This condition is treated with corticosteroids and immunosuppressive agents, such as azathioprine or cyclophosphamide.
An alternative designation for pemphigoid, a dermatological condition characterized by the formation of substantial and taut blisters, presents itself.