Any of several compounds, originally derived from prostaglandin precursors in platelets, that stimulate aggregation of platelets and constriction of blood vessels.
A substance in the body that causes constriction of blood vessels and aggregation (clumping) of platelets.
A substance produced in the blood platelets which induces aggregation of platelets and thereby thrombosis. It is also a vasoconstrictor (a substance that causes the constriction of blood vessels).
Two compounds, thromboxane A2 (TXA2) and thromboxane B2 (TXB2), exist. TXA2 is a highly potent trigger of platelet aggregation and platelet release responses. It also acts as a vasoconstrictor. Platelets produce TXA2, but it is very unstable and quickly breaks down into TXB2 through a non-enzymatic hydrolysis process. TXB2 is inactive and has a short half-life of 30 seconds.