Peyers patches

Patches of lymphoid tissue or lymphoid nodules on the walls of the ilealsmall intestine.


A special set of lymphoid organs found in the intestinal wall. They filter out antigens that enter the intestine in food or come from the bacteria growing naturally in the intestine, and “present” those intact antigens to adjacent lymphoid tissues, via special “M” cells of the Peyer’s patches. This activates the lymphocytes in the patches, which then migrate out of the node and into the blood where they float in the tissue spaces just inside the intestinal lining. There they secrete antibodies (primarily IgA), which are then transported into the lumen (contents) of the gut and attack (bind) the antigen.


Patches of lymphoid tissue on the mucous membrane of the small intestine [Described 1677. After Johann Conrad Peyer (1653-1712), Swiss anatomist.]


Group of lymph nodes near the junction of the ileum and colon; in typhoid fever and certain other infectious diseases, they typically become enlarged and sometimes ulcerated.


Oval masses of lymphoid tissue on the mucous membrane lining the small intestine.


A group of diffuse lymphoid nodules in the mucosa of the small bowel. Part of the mucosa-associated lymphoid tissue (MALT), Peyer’s patches detect and respond to foreign antigens in the gastrointestinal tract. Antibodies secreted by B cells in Peyer’s patches provide a significant defense against ingested pathogens.


Peyer’s patches are regions of mucosa-associated lymphoid tissue (MALT) located in the mucous membrane of the ileum, the final segment of the small intestine. They are part of the lymphatic system and play a role in combating infections.


 


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