Morphological changes that follow cell death, usually involving nuclear and cytoplasmic changes.
A pathological process caused by the progressive degradative action of enzymes that is generally associated with severe cellular trauma. It is characterized by mitochondrial swelling, nuclear flocculation, uncontrolled cell lysis, and ultimately cell death.
The death of cells by unprogrammed methods as opposed to apoptosis, which is a programmed death. Pyknosis (shrunken and hyperkeratosis or darkened basophilic nuclear staining), karyolysis (swollen and pale basophilic nuclear staining), and karyorrhexis (nuclear rupture or fragmentation) are typical events in necrosis of cells. The release of intracellular contents leads to an inflammatory response.
Refers to cell death caused by physical injury to the cell (e.g., exposure to toxin, exposure to ultraviolet light, lack of oxygen, etc.).
The morphological changes indicative of cell death.
The death of a part of the body such as a bone, tissue or an organ as a result of disease or injury.
Cellular changes that occur and are indicative of cellular death.
Death of some or all of the cells in a tissue; usually caused by disease, inadequate blood supply to the tissue, or injury.
Death of living cells or tissue; gangrene.
An infection that spreads extremely rapidly and travels through tissue along superficial and deep planes; treatment includes aggressive surgical debridement and antibiotics in order to prevent death.
The death of cells or tissues caused by trauma, a bum, or disease.
The death or decay of tissue in a part of the body, such as a bone. Necrosis occurs when not enough blood is supplied to tissue.
The death of some or all of the cells in an organ or tissue, caused by disease, physical or chemical injury, or interference with the blood supply. Caseous necrosis occurs in pulmonary tuberculosis, the lung tissue becoming soft, dry, and cheese-like.
Death of a limited portion of tissue, for example in bone, as the result of disease or injury, when a fragment dies and separates. A portion of brain may become necrotic after a stroke.
The death of cells, tissues, or organs. Necrosis may be caused by numerous insults to tissues (e.g., insufficient blood supply, burns, compression, pathogenic microorganisms, medications, radiation, toxins, or tissue trauma).
The passing away of a particular and well-defined portion of a flora or tissue is commonly known as “death”.
The atypical demise of cells, potentially instigated by diseases or infections.
The demise of tissue cells is termed necrosis. This can transpire due to insufficient blood supply, known as ischemia, which might result in tissue death referred to as gangrene. Other causes encompass infection, impairment from intense heat or cold, harmful chemicals, or excessive exposure to X-rays or various forms of radiation.
The visual characteristics of deceased tissue vary based on the cause of necrosis and the specific type of tissue involved. For instance, in cases of tuberculosis-induced necrosis, the deceased tissue takes on a soft, dry, and cheese-like texture. On the other hand, fatty tissue beneath the skin that has perished due to injury or infection transforms into resilient scar tissue, often giving rise to a solid nodule.
The abnormal demise of individual cells or clusters of cells that remain in contact with living tissues.
The total morphological alterations signifying cell death, resulting from the gradual breakdown by enzymes. This process can impact clusters of cells, sections of a structure, or an entire organ.