Is a peroxidase enzyme most abundantly present in neutrophil granulocytes (a subtype of white blood cells). It is an inflammatory enzyme produced by activated leukocytes that predicts risk of coronary heart disease.
An enzyme found principally in neutrophils and monocytes that generates hypochlorous acid from hydrogen peroxide and chloride ions. The enzyme is released into plasma in infectious and inflammatory diseases. Measurement of plasma levels of MPO has been used in some risk assessments for patients with acute coronary syndrome.