Monoamine oxidase A (MAOA)

Is an isozyme of monoamine oxidase. It preferentially deaminates norepinephrine (noradrenaline), epinephrine (adrenaline), serotonin, and dopamine.


An enzyme that catalyzes the oxidation of a large variety of monoamines, including epinephrine, norepinephrine, and serotonm. Monoamine oxidase is found in most tissues, particularly the liver and nervous system. Drugs that act as inhibitors of this enzyme are widely used in the treatment of depression.


 


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