Generalized tonic-clonic seizures are one of the most common childhood neurological disorders. The seizure involves synchronous bilateral electrical epileptical discharges; therefore, the first signs reflect involvement of both hemispheres of the brain. The seizure, however, can begin in a focal area of the brain (or one hemisphere) as a partial seizure and spread to other areas and become a generalized seizure. Seizures are defined as a sudden, involuntary, transient alteration in neurological function resulting from excessive electrical discharge of neurons. Generalized tonic-clonic seizures, formerly known as grand mal seizures, are the most common and dramatic of childhood seizure manifestations.