Peutz-Jeghers syndrome (PJS) is a rare, heritable condition typified by abnormal pigmentation (freckling) around and inside the mouth and hamartomatous polyps of the gastrointestinal (GI) tract. Hamartomas are benign tumors of embryonic origin and are caused by anomalous development of organ tissues.
An inherited disorder characterized by the presence of polyps of the small intestine and melanin pigmentation of the lips, mucosa, fingers, and toes. Anemia due to bleeding from the intestinal polyps is a common finding.
A rare genetic disorder where polyps form in the digestive tract, and small, flat, brown marks develop on the lips and inside the mouth. Sometimes, these polyps can bleed, lead to abdominal discomfort, or result in intussusception, where the intestine folds into itself, causing a blockage.
Diagnosis for the condition can be done through a barium X-ray and endoscopy. Polyps that bleed might be surgically removed.